Longevity, or life expectancy, is one of the most talked about topics of recent days; let’s take a look at this file.
Scientific studies have revealed that we can protect our telomeres (the protective covers at the end of our chromosomes) and increase our lifespan (healthy, active disease-free years) with changes we can make in our daily habits.
According to these studies, it is shown that sleep quality, exercise, various diets and even some chemicals deeply affect telomeres, and chronic stress, negative thoughts, tense relationships and even living in a bad environment can slowly deplete telomeres.
Here are some new and promising treatments for longevity and healthy aging:
1. Gene Therapies:
CRISPR technology aims to slow down aging through gene editing. Lengthening telomeres aims to make cells divide longer and slow down the aging process.
2. Senolytics:
Are drugs that target senescent cells and aim to clear these cells. The accumulation of such cells in the body is associated with chronic diseases and signs of aging.
3. NAD+ Supplements:
NAD+ levels decrease with aging. Supplements that increase NAD+ levels (for example, nicotinamide riboside or nicotinamide mononucleotide) may reduce signs of aging and improve cellular function.
4. Metformin and Rapamycin:
These drugs, used to treat diabetes, are being researched as having the potential to slow down aging.
5. Epigenetic Changes:
Play an important role in the aging process. Reversing these changes can rejuvenate cells and slow aging. Activation of certain genes (OCT4, SOX2, KLF4, c-MYC), known as Yamanaka factors, has the potential to rejuvenate cells by reprogramming them.
6. The Gut Microbiome:
Has a huge impact on overall health and aging. Modulation of the microbiome may be important for longevity and healthy aging.
– Probiotics, prebiotics and microbiome transplants can positively affect the aging process by improving intestinal health.
7. The Regenerative Potential Of Stem Cells:
Can be used to repair damaged tissues and reduce signs of aging. Mesenchymal stem cells, in particular, show promise in the treatment of various degenerative diseases and delaying the signs of aging.
These treatment methods are still in the research phase, and some are undergoing clinical trials. Scientific advances in this field may offer new opportunities to live a longer, healthier life in the future.
So, In This Case, What Can We Do To Protect These Telomeres?
1. Nutrition Rich in Antioxidants:
– Foods rich in antioxidants should be consumed to reduce the damage caused by free radicals in the body.
– Fresh vegetables and fruits, especially green leafy vegetables, red fruits and citrus fruits, are recommended.
2. Ph Balanced Diet:
– Maintaining pH balance in the body also means protecting all chemical events. We can reduce the acidic load on the body by consuming alkaline foods.
– Especially vegetables, fruits, nuts and seeds have alkaline properties.
3. Avoid Sugar and Refined Carbohydrates:
– Sugar and refined carbohydrates cause glycosylation. Glycosylation is also an oxidative reaction. In fact, it is a kind of combustion and oxidation reaction. Glycosylation and aging are somehow the same thing. In this case, such foods cause faster aging.
4. Regular Exercise:
-Regular exercise is beneficial for both physical and mental health. In studies conducted for Alzheimer’s, it has been found that there is a negative correlation between increasing muscle mass in the body and regular muscle functioning and Alzheimer’s and dementia.
-It is a recommended sport to exercise with high heart rate variability, increasing the ability of the autonomic nervous system to adapt to environmental changes.
5.Stress Management :
-Stress management techniques such as meditation, yoga and breathing exercises are important in helping us cope with stress. Stress tires out our mitochondria, the energy system in our cells.
6. Social and Mental Health:
– Social ties and supportive relationships have positive effects on longevity. At the same time, mental health and happiness also affect life expectancy. Good relationships, a sense of compassion, environmental awareness, and balance in dopamine serotonin levels are very important.
7.Detoxification:
– We recommend detoxing at regular intervals to support the body’s detoxification processes. No matter how healthy we eat, our body produces toxins as waste, and detoxification is important in order to get rid of these toxins.
-It is recommended to drink plenty of water, consume herbal teas and consume foods that support detoxification.
8. Adequate and Quality Sleep:
– Maintaining sleep patterns and getting quality sleep is critical for healthy aging. Our entire body restarts itself during sleep. A quality sleep ensures the healthy functioning of all our body organs, including skin, hair and nails.
9. Supplements and Vitamins:
– Sometimes, no matter what we do, we cannot meet the required amount of vitamins and minerals for our body. This causes us to live in low battery mode and causes us to gradually age. It is recommended to take vitamin and mineral supplements when necessary. Especially the importance of vitamin D, omega-3 fatty acids, magnesium and B vitamins is emphasized.
10. Gut Health:
– Gut health has a huge impact on overall health and longevity. A diet enriched with probiotics and prebiotics is important. In individuals who contain sufficient amounts of fiber and whose intestinal activity and intestinal wall are intact, the amount of toxins will circulate less, thus ensuring the proper functioning of all systems.
Since we can no longer provide enough vitamins, minerals and energy-supporting treatments with food, we need to supplement them from time to time, either orally or intravenously. Today’s conditions interrupt the continuity of taking these oral supplements, especially in the active working population. Intestinal absorption disorders (intestinal epithelial barrier permeability, microbiota disorder, inflammatory bowel diseases). Some side effects may cause side effects such as nausea, vomiting, bad taste in the mouth, and diarrhea. Therefore, performing some supportive treatments intravenously both improves the quality of life and prevents damage to our telomeres.
WHAT DO WE GIVE THROUGH IV?
Myers cocktail (b1,b2,b3,b5,b6,b12,magnesium,vitamin C)
Chronic fatigue, general reluctance, depression, fibromyalgia, relief of acute & chronic stress effects, migraine, anxiety, skin health, old age, addiction
After application;
Pain level decreases, fatigue decreases. Daily mobility increases. Patient energy levels increase rapidly.
Glutathione (the most important endogenous antioxidant in the body)
Glutathione is found naturally in the body. The main functions of glutathione are:
-Glutathione protects cells from damage and helps prevent aging and various diseases.
-Glutathione binds and removes toxins, heavy metals and harmful chemicals from the body.
-Glutathione supports the proper functioning of the immune system
-It plays a role in energy production and protein synthesis of cells. It also helps regenerate and repair cells.
-Glutathione supports the function of many enzymes necessary for DNA synthesis and repair.
Glutathione levels can be affected by factors such as aging, poor nutrition, stress, infections and exposure to toxins.
ALA (alpha lipoic acid)
Alpha lipoic acid (ALA), a fatty acid that plays a role in energy metabolism within the cell, is an organic substance found in all human cells. Alpha lipoic acid, synthesized in mitochondria, the center of energy production, functions as an antioxidant that prevents inflammation and aging.
If we were to make a definition for alpha lipoic acid, it is an auxiliary molecule located in the mitochondria that enables biochemical reactions in the body to occur. They are the power plants of thousands of cells. It is naturally present in our body, but since it is not in sufficient quantity, it must be supplemented with foods. If we cannot make it in sufficient amounts, then ALA supplements come to the fore.
VITAMIN C
Vitamin C (Ascorbic Acid) is a water-soluble antioxidant that increases extracellular collagen production and is important for the function of immune cells. Vitamin C levels in the body are kept under control by the intestines and kidneys. Due to these systems, vitamin C is not stored in the body and is excreted from the body. When vitamin C is taken orally, its absorption decreases depending on the dose and the maximum achievable plasma vitamin C concentration is approximately 0.6-2.0 mg/dL. On the other hand, when ascorbic acid is injected intravenously or i.v. When given by infusion, pharmacological vitamin C concentrations can be increased to levels of 20-200 mg/dL (100 times higher).
Vitamin C supports the adrenal gland and maintains the body’s energy level. It strengthens the immune system, improves bone health, and increases skin collagen. It reduces the side effects of these treatments in cancer patients receiving chemotherapy and radiotherapy. It provides chronic fatigue, anemia, osteoporosis, depression, Alzheimer’s, wound healing, skin support and color equalization, and hormone regulation.
NAD (NICOTINAMIDE ADENINE DINUCLOTIDE)
It is the coenzyme that provides energy production in our body. It converts the energy we get from food to the cellular level and ensures its use. As it is known, the energy needs of our cells are met by ATP. The life cycle comes and goes on this energy flow. In other words, when we eat, in order for this energy in the food to be converted into ATP, they must release hydrogen to the area we call the electron transport chain, so that oxidative phosphorylation can be achieved. This is our NAD, it carries the hydrogen in food to the cell, while carrying it, it becomes NADH and enters the production of ATP. Only ATP cannot be stored in the body, so when the NADH ratio is high, the unstorable ATP returns and is stored as fat. In other words, the more NAD we have, the more energy we need. Scientific studies report that the NAD/NADH ratio should be around 700.
The higher the amount of NAD, the more the body regenerates itself.
Newly discovered sirtuins, also known as ‘guardians of genes’, play a vital role in maintaining cellular health. Sirtuins are involved in cellular stress responses and damage.
It is a family of enzymes involved in repair. It also affects insulin secretion and aging processes and
They also play a role in aging-related health problems such as neurodegenerative diseases and diabetes.
NAD+ is the fuel that helps sirtuins maintain genome integrity and support DNA repair.
So, if our body produces NAD, why should we take NAD intravenously or orally?
Yes, our body produces NAD, but as we age, our coenzyme levels decrease and our DNA can break more easily. This causes cellular changes that cause aging. The more NAD is in our body, the more it affects the mitochondria and increases the length of telomeres, which can delay aging. When cellular energy is high, immunity against diseases is more resistant, when serotonin-dopamine levels are balanced, cognitive functions are more active, and depression and anxiety are less.
B1 (Thiamine)
This vitamin, which is absorbed from the intestine, is easily affected by absorption disorders in the intestine. Eating disorders, some liver diseases, Crohn’s disease, celiac disease and alcohol addiction can cause vitamin B1 deficiency. Those who consume too much coffee, black tea or raw fish may not be able to fully absorb vitamin B1 from food. Some ingredients in these foods inhibit the absorption of vitamin B1. Symptoms of vitamin B1 deficiency are: Psychological disorders due to damage to nerve cells, forgetfulness, confusion, burning in the feet, stinging sensation, loss of sensation, muscle aches and difficulty in moving, sleep disorders, fatigue, loss of appetite, weight loss, digestive system diseases (bloating, constipation, etc.), heart diseases, skin diseases, visual disorders and chronic fatigue. Moreover, its deficiency does not show up directly in laboratory tests. The level of transketolase enzyme, a special enzyme, is also related to this vitamin.
B2 (Riboflavin)
Vitamin B2 is an antioxidant, cofactor in liver detoxification stages,
It is the precursor of FMN and FAD. FAD (Flavin adenine dinucleotide) has a strong antioxidant effect.
Glutathione provides regeneration. In its deficiency, migraines, cataracts, dry skin, autism, canker sores in the mouth, red tongue and lips, environmental light and heat sensitivity, and iron deficiency may occur.
Dexpanthenol (pro B5)
Dexpanthenol is easily converted into pantothenic acid, which is distributed in body tissues.
It functions in the highest concentration in the liver, adrenal glands, heart and kidneys. Absorption is achieved through the intestine. The dose taken orally is sufficient for individuals with healthy intestines. However, vitamin B5 deficiency is frequently observed in people with intestinal malabsorption. It is manifested by skin dryness, aging and loss of elasticity.
Vitamin B12
Vitamin B12, also known as cobalamin, is a vitamin that is vital for the body. Its main functions are: Production of Red Blood Cells, it is a critical component in DNA synthesis and repair processes. Necessary for the proper functioning and proliferation of cells, vitamin B12 protects the health of nerve cells and plays an important role in the formation of the myelin sheath (the structure that protects nerve cells and accelerates nerve conduction). Its deficiency may decrease cognitive functions.
In its deficiency, fatigue and weakness, anemia, neurological problems (numbness, tingling, balance problems), memory and thinking problems, depression and other psychiatric symptoms may occur.
MAGNESIUM
Magnesium is a mineral vital to the healthy functioning of the body and has several biological functions:
It plays a role in ATP (adenosine triphosphate) production and cellular energy metabolism. It is a necessary component in the conversion of amino acids into proteins in Protein Synthesis. It regulates muscle contractions and supports the transmission of nerve signals. It protects the strength of the bone structure and allows calcium to settle in the bones. It plays a role in the synthesis and repair of genetic material (DNA, RNA). It serves as a co-factor for the proper functioning of hundreds of enzymes that enable biochemical events in our body. It helps blood vessels relax and blood pressure decreases.
